Roberts, Akanksha and Shahdeo, Deepshikha and Gandhi, Sonu (2020) Advancement of Immobilization Techniques in Forensic Science. In: Immobilization Strategies. Springer, pp. 475-507.
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Immobilization Strategies Biomedical, Bioengineering and Environmental Applications by Anuj Tripathi Jose Savio Melo (z-lib.org).pdf Download (18Mb) | Preview |
Abstract
Immobilization techniques involve the confining/anchoring of a molecule (enzyme or cells) in or on an inert support/substrate matrix for stability, increased efficiency and easy recoverability of the molecule. The immobilization of molecules to a substrate is carried out on the basis of five major principle methods, i.e. adsorption, entrapment, membrane confinement (encapsulation), cross-linking (copolymerization) and covalent binding. Various different scientific processes make use of immobilization techniques to increase the efficiency of the process. In the upcoming field of forensic science, which involves the application of scientific methods to matters under investigation by a court of law, there has been advancement in the immobilization techniques being used to solve various cases. This involves both qualitative and quantitative analyses. Immunoassays, biosensors, adsorption and chromatographic methods make use of immobilization of molecules and are used for various forensic analyses such as narcotic drug, poison, toxin, heavy metal and pesticide detection, serological, latent fingerprinting analysis of biomolecules. In this chapter, we shall discuss in detail the different types of immobilization techniques, principle and their applications in forensic science.
Item Type: | Book Section |
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Subjects: | Animal Genetics and Genomics Infectious Diseases Inflammation Biology Reproductive Biology Genetic Engineering Bioinformatics |
Depositing User: | Mr Harjit Singh |
Date Deposited: | 22 Jun 2021 11:22 |
Last Modified: | 22 Jun 2021 11:22 |
URI: | http://niab.sciencecentral.in/id/eprint/98 |
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